Here we review exometabolomics approaches and applications to show how this simple technique can provide critical insights into phenotypes, cellular interactions and environmental transformations. We highlight how this approach can be used in rapid phenotyping assays that are becoming popular in drug development, synthetic biology, biofuel development, and investigating the […]
News
14 posts
In this article we describe the development of a simple soil metabolomics workflow and a novel spike recovery approach for the analysis of soil organic matter (SOM). The cycling of SOM by microorganisms is a critical component of the global carbon cycle but remains poorly understood. There is an emerging […]
The role that pharmaceutical antibiotics play within the producing organism has remained a largely unexplored field as the research focus has mainly revolved around high production for therapeutic use. Evidence exists to suggest that, at low levels, these “antibiotics” may actually act as signaling or regulatory molecules within or between cells. Julian Davies, a […]
Understanding microbial metabolite cycling in soils using novel metabolomics approaches Trent Northen, Staff Scientist Lawrence Berkeley National Laboratory Berkeley, CA To improve agricultural processes and combat the effects of desertification and drought, we urgently need to improve our understanding of terrestrial nutrient cycling in soils. We have major investments in […]