Category Archives : News

Gao et al publish on Application of Black Silicon for Nanostructure-Initiator Mass Spectrometry in Analytical Chemistry

Since the development of nanostructure-initiator mass spectrometry (NIMS), we have been working to find a way of producing these surfaces without the use of electrochemical HF etching, which poses both major safety implications and greatly limits the wide-spread implementation of NIMS. Here, we show that inductively coupled plasma (ICP) reactive ion etching (RIE), a common, […]

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de Raad et al publish review on high-throughput MS-based platforms and their potential application in metabolomics

Here we highlight current high-throughput MS-based platforms and their potential application in metabolomics. Although current MS platforms can reach throughputs up to 0.5 seconds per sample, the metabolite coverage of these platforms are low compared to low-throughput, separation-based MS methods. High-throughput comes at a cost, as it’s a trade-off between sample throughput and metabolite coverage. We discuss […]

Baran et al publish on exometabolite niche partitioning in soil bacteria in Nature Communications

Here we examine the exometabolite composition of desert biological soil crusts (biocrusts) and the substrate preferences of seven biocrust isolates. The biocrust’s main primary producer releases a diverse array of metabolites, and isolates of physically associated taxa use unique subsets of the complex metabolite pool. Individual isolates use only 13−26% of available metabolites, with only […]


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Silva et al publish review on exometabolomics and mass spec imaging in Current Opinion in Biotechnology

Here we review exometabolomics approaches and applications to show how this simple technique can provide critical insights into phenotypes, cellular interactions and environmental transformations. We highlight how this approach can be used in rapid phenotyping assays that are becoming popular in drug development, synthetic biology, biofuel development, and investigating the metabolic interactions and dependencies of […]

Julian Davies visits Potter Street Lab at LBNL

The role that pharmaceutical antibiotics play within the producing organism has remained a largely unexplored field as the research focus has mainly revolved around high production for therapeutic use.  Evidence exists to suggest that, at low levels, these “antibiotics” may actually act as signaling or regulatory molecules within or between cells.  Julian Davies, a veteran in the field of […]

Northen awarded DOE Early Career Award to develop soil exometabolomics

Understanding microbial metabolite cycling in soils using novel metabolomics approaches Trent Northen, Staff Scientist Lawrence Berkeley National Laboratory Berkeley, CA To improve agricultural processes and combat the effects of desertification and drought, we urgently need to improve our understanding of terrestrial nutrient cycling in soils. We have major investments in soil sequencing efforts that has […]