Northen Lab researcher Jenny Onley attended the 2022 ASM Microbe conference this past June, presenting the poster “High-Throughput and Bond-Specific Analysis of Lignocellulose Deconstructing Enzymes with LignoChip.” This technology was developed by a team of scientists including other lab members Kai Deng, Noel Ha, Markus de Raad, and Trent Northen. […]
publications
31 posts
The JGI metabolomics group and Northen Lab members (including Katherine Louie, Benjamin Bowen, Andrea Kuftin, and Trent Northen) have contributed to multiple recent papers. Some of the highlights include the following: Novel metabolic interactions and environmental conditions mediate the boreal peatmoss-cyanobacteria mutualism [1] Sphagnum (or peat moss) forms symbiotic relationships […]
Northen Lab researchers Markus de Raad, Peter Andeer, Suzanne Kosina, Nicholas Saichek, Amber Golini, La Zhen Han, Ying Wang, Benjamin Bowen, and Trent Northen are authors on the paper “A Defined Medium for Cultivation and Exometabolite Profiling of Soil Bacteria.” Traditional media for microbial growth do not take into account […]
Northen Lab researchers Ying Wang, Tami Swenson, Anita Silver, Peter Andeer, Amber Golini, Suzanne Kosina, Benjamin Bowen, and Trent Northen are authors on the new paper “Substrate Utilization and Competitive Interactions Among Soil Bacteria Vary With Life-History Strategies.” This paper looks at genomic traits, exometabolite profiles, and interactions among soil […]
Northen Lab researchers Suzanne Kosina, Markus de Raad, Benjamin Bowen, and Trent Northen are authors on the paper “Biofilm Interaction Mapping and Analysis (BIMA) of Interspecific Interactions in Pseudomonas Co-culture Biofilms.” BIMA is an integrated platform that utilizes automated colony printing, barcoded mutant library profiling, and metabolomics to investigate biofilm-based […]
Northen Lab researchers Vanessa Brisson, Benjamin Bowen, Amber Golini, and Trent Northen are authors on the new paper “Identification of Effector Metabolites Using Exometabolite Profiling of Diverse Microalgae.” In this study, untargeted metabolomic analysis was conducted on nonpolar exometabolites produced by four microalgal strains. Understanding microalgal interactions is important, given […]
Lauren Jabusch, Benjamin Bowen, and Trent Northen are authors on the paper “Microfabrication of a Chamber for High-Resolution, In Situ Imaging of the Whole Root for Plant–Microbe Interactions.” As mentioned before, specialized plant growth chambers offer promise as a way of investigating rhizosphere interactions. The Imaging EcoFAB, presented in this […]
The rhizosphere is a dynamic ecosystem that is difficult to study due to the volume and types of interactions that occur. Trent Northen is an author on the review paper “Specialized Plant Growth Chamber Designs to Study Complex Rhizosphere Interactions” that takes a look at different types of chambers and […]
Northen Lab researchers Tami Swenson, Marc Van Goethem, and Trent Northen are authors on the paper “Learning representations of microbe-metabolite interactions” [1]. This research focuses on the integration of multiomics datasets and methods of finding relationships between microbial genes and metabolomes. A Matters Arising article by Quinn and Erb responded […]
Northen Lab researchers Nicole Ing, Kai Deng, and Trent Northen are authors on a paper examining glycoside hydrolases, or GHs. GHs are capable of hydrolyzing (or breaking down) polysaccharides, which make them an important compound for bioenergy production. A subfamily of GHs, GH5_4, can hydrolyze cellulose, xyloglucan, and mixed-linkage glucans […]
JGI Metabolomics researchers Andrea Kuftin, Katherine Louie, and Trent Northen contributed to the paper “Development of platforms for functional characterization and production of phenazines using a multi-chassis approach via CRAGE,” which utilized metabolomics to analyze PCA (phenazine-1-carboxylic acid) and PDC (phenazine-1,6-dicarboxylic acid) from bacterial cultures. As previously highlighted, CRAGE (or […]
Northen Lab researchers Marc Goethem, Andrew Osborn, Ben Bowen, Tami Swenson, and Trent Northen are authors on the recently published paper “Long-read metagenomics of soil communities reveals phylum-specific secondary metabolite dynamics.” Key to this paper are biosynthetic gene clusters, or BGCs, which are groups of genes that encode a metabolic […]